
Summary
GBED n/n, HERDA n/n, HYPP n/n, MH n/n, PSSM1 n/n,
MYHM n/n (UC Davis)
Color: A/A, E/e, nd1/nd2, CR/n, W20/n
Temperament: Curious, Two Curiosity variants; horse may be more curious than vigilant.
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Gait: Neg for DMRT3 No DMRT3 variants; likely non-gaited (*variants for novel "gait" abilities are currently in research).
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Sprint: Two Sprint type variants; horse may accel at short distance, quick bursts of speed over endurance type activity.
Horse has not tested positive for any known disease variants on this panel.
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Buckskin
Bay (A, E) + Cream (CR). Buckskin is the combination of at least one Black (E), at least one Agouti/Bay (A) and one Cream (CR) variant. The Bay color will be diluted by the Cream causing Buckskin. The range of Buckskins include a very dark brown to a very light buttermilk golden color. The stark black 'points' are left undiluted. Buckskins are often confused with duns, which can have a similar coat color. However, buckskins lack the 'primitive' markings of the dun unless they also have the non-Dun
Primitive Markings variant (nd1). Buckskins will pass Cream to 50% of any offspring. They will also pass Black (E) and/or Agouti/Bay (A) to at least 50% of any offspring (depending if they are Ee, Aa, or EE, Aa, or EE, AA).
Dominant White 20 (W20) - W20/n
W20/n - One Dominant White 20 (W20) variant detected; may result in White markings. Horse has 50% chance of passing to any offspring.
Cream (CR) - CR/n
CR/n - One Cream (CR) variant detected. Cream is a partial dominant and may dilute base coat color (Buckskin, Palomino, Smoky Black, etc). Horse has 50% chance of passing to any offspring.
Coat Color
Agouti (A) - A/A ASIP Likely Affected
A/A - Two Dominant Agouti variants detected. Agouti (which causes "Bay" on black) restricts black pigment to the outer regions of the body, the legs, mane & tail, nose, ear tips causing the otherwise black horse to appear "Bay". Agouti is invisible on the red based coat.
Black (E) - E/e MC1R Black Based
E/e - One Black variant and one Red variant detected.
Modifiers
Grey (G) - n/n STX17A Negative
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Brindle (BR1) - n/n MBTPS2BR1 Negative
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non-Dun Primitive Markings (nd) - nd1/nd2 TBX3 Possibly Affected
nd1/nd2 - One non-Dun Primitive Markings variant detected. Non-Dun Primitive Markings can appear as a dorsal stripe, leg barring, shadows on the face and shoulders even in the absence of the Dun variant.
Dilutes
Cream (CR) - CR/n SLC45A2 Likely Affected
CR/n - One Cream variant may dilute the base coat color to appear lighter resulting in a Palomino, Buckskin or other lightened coat color.
Champagne (CH) - n/n SLC36A1 Negative
Silver (Z) - n/n PMEL17 Negative
Pearl (PRL) - n/n SLC45A2 Negative
Dun (D) - n/n TBX3 Negative
Whites
Dominant White 20 (W20) - W20/n KIT Possibly Affected
W20/n - One Dominant White 20 variant detected. Likely white markings.
Frame/Lethal White Overo (LWO) - n/n EDNRB Negative
Leopard Complex Spotting (LP) - n/n TRPM1 Negative
Pattern 1 (PATN1) - n/n RFWD3 Negative
Sabino1 (SB1) - n/n KIT Negative
Tobiano (TO) - n/n ECA3 Negative
Splashed White (SW1) - n/n MITF Negative
Splashed White (SW2) - n/n PAX3 Negative
Splashed White (SW3) - n/n MITF Negative
Splashed White (SW4) - n/n PAX3 Negative
Health Variants - Color Related Risk
Lethal White Overo (LWO) - n/n EDNRB Negative
Congenital Stationary Night Blindness (CSNB) -n/n
Multiple Congenital Ocular Anomalies (MCOA) -n/n
Immune System
Foal Immunodeficiency Syndrome (FIS) - n/n SLC5A3 Negative
Severe Combined Immunodeficiency (SCID) - n/n DNAPK Negative
West Nile Virus Symptom Susceptibility Risk (WNVR) - n/n OAS1 Negative
Muscle Disorders
Glycogen Branching Enzyme Deficiency (GBED) -n/n
Hyperkalemic Partial Paralysis (HYPP) - n/n SCN4A Negative
Malignant Hyperthermia (MH) - n/n RYR1 Negative
Myotonia (MYT) - n/n CLCN4 Negative
Polysaccharide Storage Myopathy type 1 (PSSM1)- n/n
Neurologic Disorders
Cerebellar Abiotrophy (CA) - n/n MUTYH Negative
Lavender Foal Syndrome (LFS) - n/n MYO5A Negative
Reproductive Disorders
Androgen Insensitivity Syndrome (AIS) - n/n AR Negative
Impaired Acrosomal Reaction - Subfertility Risk (IAR) - iar/n,iar/n
Skin, Hoof and Connective Tissue Disorders
Hereditary Equine Regional Dermal Asthenia (HERDA) - n/n
Junctional Epidermolysa Bullosis type 1 (JEB1) - n/n
Junctional Epidermolysa Bullosis type 2 (JEB2) - n/n
Perform and Abilities
Gait Type Non-"Gaited" DMRT3 DMRT3 Detected
Performance Sprint MSTN Likely Affected
Temperament Curious DRD4 Detected
Two Curiosity variants; horse may be more curious than vigilant.